Carol A. Kumamoto

The paper identifies an inducible microfold-like cell population in the colon associated with severe Clostridioides difficile infection susceptibility and shows its role in epithelial repair and immune response.

This study develops a co-culture system to study C. difficile interaction with human intestinal epithelium and finds CCL20 expression is upregulated in response to the bacterium.

This study shows that Candida albicans colonization reduces ethanol consumption and alters dopamine signaling and behavioral responses in mice through prostaglandin E2.

This study develops a method to visualize single-cell phenotypic heterogeneity in gut microbial communities using spectrally compatible reporters, revealing subpopulation behavior in Clostridioides difficile during infection.

This study shows that repeated ethanol exposure of Candida albicans leads to strains with increased ethanol tolerance and reduced fluconazole susceptibility.

This paper describes an engineered E. coli system that senses Candida albicans via HPA and inhibits hypha formation to reduce virulence.