G. Valentin Börner

This study identifies a proteasome function that drives centromeric cohesin removal during meiosis II independently of separase activation, revealing a dual role for the proteasome in chromosome segregation.

The paper shows that heat stress blocks meiosis in yeast by impairing Holliday junction resolution, dependent on H3K79 methylation and a meiotic recombination checkpoint.

The paper develops an agent-based model to simulate homolog pairing during meiosis, identifying chromosome number, size, movement velocity, and repulsive forces as key factors in pairing efficiency.

The paper investigates the temporal and functional relationship between synaptonemal complex (SC) morphogenesis and recombination during meiosis in budding yeast, showing SC's role in regulating recombination transitions.

This paper shows that Rad51-mediated interhomolog recombination in budding yeast meiosis is inhibited during Phase 1 to prevent competition with Dmc1, and is promoted by the checkpoint and Pif1 helicase.