ImmunologyPLoS PathogensPeer-reviewed
Autoimmunity associated allele of tyrosine phosphatase gene PTPN22 enhances anti-viral immunity
Robin C. Orozco, Kristi Marquardt, Isaraphorn Pratumchai…·Linda A. Sherman
The study shows that the PTPN22 1858C>T allele, linked to autoimmunity, enhances anti-viral immunity by improving CD4 T cell responses and CD8-cDC function during LCMV infection.