The STAT3-VDAC1 Axis Modulates Mitochondrial Function and Plays a Critical Role in the Survival of Acute Myeloid Leukemia Cells
Kellen B. Gil, Jamie L. Borg, Rosana Moreira Pereira…·Maria L. Amaya
Author
University of Colorado AnschutzORCID 0000-0001-6478-4244Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Kellen B. Gil, Jamie L. Borg, Rosana Moreira Pereira…·Maria L. Amaya
William M. Showers, Jairav Desai, Stephanie Gipson…·Austin E. Gillen
scExploreR provides a user-friendly platform for non-programmers to analyze multimodal single-cell data with customizable plots and seamless handling of different input formats.
Mark Jordan Althoff, Mohd Minhajuddin, Brett M. Stevens…·Craig T. Jordan
This study identifies IRF2BP2 cytoplasmic sequestration by MCL1 as a mechanism driving venetoclax and azacitidine resistance in AML through ACSL1 derepression.
Anagha Inguva Sheth, Krysta L. Engel, Hunter Tolison…·Craig T. Jordan
This study identifies mitochondrial calcium utilization as a metabolic requirement of venetoclax-resistant acute myeloid leukemia stem cells and shows that targeting mitochondrial calcium uptake can eradicate these cells.