Kristen J. Radford

The paper integrates single-cell RNA sequencing data across cancer types to resolve cDC2 heterogeneity and identify major DC populations in human tumours.

This paper develops an in vitro protocol to generate human dendritic cells from iPSC with a feeder-free expansion step, resulting in DC1-like cells that show functional characteristics similar to monocyte-derived DCs.

This paper shows that AXL inhibits cholesterol mobilization in dendritic cells, which is necessary for their maturation and immunogenic response to cancer.