Author

Zhenfei Li

Chinese Academy of SciencesORCID 0000-0001-6520-431XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Denglong WuiD· 2 shared Hanchu YeiD· 2 shared Xinan WangiD· 2 shared Ziqun Liu· 2 shared Chen Wang· 1 shared Chengchao Ruan· 1 shared Chunqiao SuniD· 1 shared Chunyi Zhang· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

Denglong WuORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 9, 2026

scPRIME-seq uncovers synchronized multimodal molecular collapse facilitated by pre-neoplastic epigenetic burden in prostate cancer

Shengdi Li, Ziqun Liu, Yingying Xie…·zhenfei li

The paper introduces scPRIME-seq, a multimodal single-cell platform, and finds pre-neoplastic epigenetic changes drive tumor progression in prostate cancer.

DOI 10.64898/2026.10.07.757464

humanscRNA-seq

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Cancer BiologybioRxivPreprintSep 2, 2026

A patient-centric therapeutic paradigm uncouples prostate cancer suppression from systemic metabolic collapse

Ziqun Liu, Hanchu Ye, Haoran Hu…·Zhenfei Li

This paper identifies metabolic dysregulation caused by abiraterone in prostate cancer patients and develops Lifehug-9892 to suppress tumors while preserving systemic metabolic health.

DOI 10.64898/2026.08.30.748180

humanmetabolomics

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Cancer BiologySignal Transduction and Targeted TherapyPeer-reviewedSep 28, 2024

Epigenetic reader ZMYND11 noncanonical function restricts HNRNPA1-mediated stress granule formation and oncogenic activity

Lian Cheng, Chunyi Zhang, Pan Wen Tian…·Gong‐Hong Wei

This study identifies a noncanonical function of ZMYND11 as an arginine-methylated HNRNPA1 reader that suppresses stress granule formation and tumor progression.

28 citations

humanproteomics

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