Viraj R. Sanghvi

This study identifies a dietary lipid axis driven by linoleic acid and FADS2 that suppresses antitumor immunity in liver cancer, offering a therapeutic target for immunotherapy resistance.

This study identifies mRNA glycation by methylglyoxal as a metabolic stress sensor, showing impaired translation and beta-cell dysfunction, which is mitigated by metformin.

This study identifies SLC4A11 as a mediator of ammonia import in hepatocellular carcinoma, showing its role in promoting cancer stemness and tumor growth.

This study identifies RAP2 GTPase as a central integrator of cytoskeletal signals in Hippo pathway regulation, showing its role in mediating responses to cytoskeletal changes and its impact on Hippo kinase activity.