Stressostat cultivation of Lactococcus lactis improves lactate stress resistance through mutations in RNA polymerase
Sylviani Hartono, Henriette Lyng Røder, Sjef A. Boeren…·Oscar van Mastrigt
The paper isolates lactate-resistant Lactococcus lactis variants using stressostat cultivation and identifies RNA polymerase mutations as key drivers of resistance through proteome changes.