Author

Alfredo Smiriglia

University of FlorenceORCID 0000-0001-6654-3962Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Assay:metabolomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea MorandiiD· 2 shared Albert Coll‐Manzano· 1 shared Alessia CorradoiD· 1 shared Alexandra AvgustinovaiD· 1 shared André C. MülleriD· 1 shared Angela BachiiD· 1 shared Angela SubbianiiD· 1 shared Antoni Gañez ZapateriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCell Biology

Andrea MorandiORCID

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2 papers

Recent·Most cited

Cell BiologyAdvanced SciencePeer-reviewedApr 21, 2026

Nuclear metabolism oscillation during the cell cycle reveals a link between the phosphatidylinositol pathway and histone methylation.

Antoni Gañez Zapater, Savvas Kourtis, Camilla Reiter Elbæk…·Sara Sdelci

This study identifies cell cycle-dependent nuclear phosphatidylinositol metabolism and its impact on histone methylation and heterochromatin states.

2 citations

humanproteomics

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Cancer BiologyEMBO Molecular MedicinePeer-reviewedJun 26, 2024

FADS1/2-mediated lipid metabolic reprogramming drives ferroptosis sensitivity in triple-negative breast cancer

Nicla Lorito, Angela Subbiani, Alfredo Smiriglia…·Andrea Morandi

The paper identifies FADS1/2-mediated lipid metabolic reprogramming as a driver of ferroptosis sensitivity in triple-negative breast cancer, showing that high FADS1/2 expression correlates with poor prognosis and susceptibility to ferroptosis-inducing agents.

118 citationstop 1%

humanbulk RNA-seq

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