Author

Lefan Yu

Centre National de la Recherche ScientifiqueORCID 0000-0001-6659-3118Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1

Frequent Co-Authors

Aldo R. Camacho‐ZarcoiD· 1 shared Damien Maurin· 1 shared Guillaume BouvigniesiD· 1 shared Martin J BlackledgeiD· 1 shared Nadia NaffakhiD· 1 shared Rob W. H. RuigrokiD· 1 shared S. CusackiD· 1 shared Selin Ece DedeoğluiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aldo R. Camacho‐ZarcoORCID

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1 paper

Recent·Most cited

BiochemistryJournal of the American Chemical SocietyPeer-reviewedSep 14, 2023

Multivalent dynamic colocalization of avian influenza polymerase and nucleoprotein by intrinsically disordered ANP32A reveals the molecular basis of human adaptation

Aldo R. Camacho‐Zarco, Lefan Yu, Tim Krischuns…·Martin J Blackledge

This study identifies how the E627K mutation in avian influenza polymerase enables multivalent colocalization with ANP32A and nucleoprotein in human cells, facilitating viral adaptation.

14 citations

humanmouse

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