Annabelle Varrot

This study investigates how different norovirus genotypes recognize human milk oligosaccharides using structural and biochemical methods, revealing genotype-specific binding mechanisms.

This study identifies ITGB1 and MRC2 as host factors involved in bronchial epithelial cell antifungal activity through interactions with A. fumigatus lectin FleA, revealing two pathways that inhibit fungal filamentation.

This paper characterizes Trichuris suis HEX-2, a β-hexosaminidase, through bioinformatics, enzymatic assays, and structural analysis, revealing its substrate specificity and structural similarities to human enzymes.

This study characterizes Cucumis melo agglutinin (CMA1), revealing its glycan-binding specificity and 3D structure, and compares it to the R-type lectin RCA1.

This paper presents a cell-free expression method for multivalent rhamnose-binding lectins and demonstrates their direct analysis using biolayer interferometry for binding affinity and specificity.