Katherine F. Roby

This study identifies IRAK1 as a key mediator of LMW HA-induced stemness in EOC, showing its role in chemoresistance and demonstrating TCS2210 as a potential inhibitor.

The paper identifies ERβ-regulated genes in granulosa cells that are essential for ovarian follicle maturation beyond the antral stage, revealing both known and novel genes involved in this process.

The paper investigates the role of ovarian KISS1 signaling in oocyte maturation and shows that ERβ regulates KISS1 expression in granulosa cells, which is essential for gonadotropin-induced oocyte maturation.

This study shows that ESR2 prevents excessive activation of primordial follicles, and its disruption leads to premature ovarian senescence and reduced AMH and estradiol levels.