David Annandale Johnston

This study shows that Medihoney and a sugar-free Manuka honey extract inhibit Substance P-induced mast cell degranulation by suppressing MRGPRX2 activation, suggesting their potential as therapies for IC/BPS.

The paper develops assembloid models of esophageal adenocarcinoma using tumor organoids and fibroblasts to study the tumor microenvironment.

This study shows that in bone marrow stromal cells, matrix deformations and differentiation are influenced by ECM stiffness, geometry, and cell density, with high cell density reducing deformation differences between stiff and soft substrates.

The paper identifies a novel short ACE2 isoform expressed in respiratory epithelia that is upregulated by interferon and RNA virus infection but not SARS-CoV-2, and shows reduced SARS-CoV-2 binding affinity.