Liliya Nazlamova

The paper develops assembloid models of esophageal adenocarcinoma using tumor organoids and fibroblasts to study the tumor microenvironment.

The paper identifies a novel short ACE2 isoform expressed in respiratory epithelia that is upregulated by interferon and RNA virus infection but not SARS-CoV-2, and shows reduced SARS-CoV-2 binding affinity.

This paper presents a high-throughput imaging assay for characterizing PRPF31 missense variants using CRISPR-edited cells, providing evidence for variant classification.

The paper uses in silico, in vitro, and clinical approaches to assess the pathogenicity of a novel missense variant in PRPF31 associated with retinitis pigmentosa.