Cell BiologyScience AdvancesPeer-reviewed
Epigenetic regulation of p63 blocks squamous-to-neuroendocrine transdifferentiation in esophageal development and malignancy
Yongchun Zhang, Dimitris Karagiannis, Helu Liu…·Jianwen Que
This study shows that p63 regulates the balance between squamous and neuroendocrine cell fates in esophageal development and cancer by modulating epigenetic mechanisms.