Author

Sarah Preston‐Alp

The Wistar InstituteORCID 0000-0001-6807-2244Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew V. KossenkoviD· 2 shared Davide MaestriiD· 2 shared Italo TemperaiD· 2 shared Lisa Beatrice CarusoiD· 2 shared Paul M. LiebermaniD· 2 shared Samantha S. SoldaniD· 2 shared Asher A. Sobotka· 1 shared Benjamin E. GewurziD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersMicrobiology

Andrew V. KossenkovORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedFeb 10, 2026

Integrated transcriptomic and methylome analysis reveals retinoic acid pathway activation after decitabine treatment in EBV associated gastric cancer

Sarah Preston‐Alp, Yin Wang, Matteo Bergonzoni…·Italo Tempera

The paper investigates the effects of decitabine on EBV-associated gastric cancer by integrating transcriptomic and methylome data, revealing retinoic acid pathway activation as a potential therapeutic target.

2 citations

humanDNA methylation

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Cancer BiologyJournal of Medical VirologyPeer-reviewedJul 1, 2025

PARP1 Inhibition Halts EBV+ Lymphoma Progression by Disrupting the EBNA2/MYC Axis

Lisa Beatrice Caruso, Giorgia Napoletani, Samantha S. Soldan…·Italo Tempera

This study shows that PARP1 inhibition reduces EBV-driven lymphoma progression by disrupting the EBNA2/MYC axis in a mouse model.

6 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintOct 14, 2021

Interferon-gamma Induces Melanogenesis Via Post-Translational Modification of Tyrosinase

Xuan Mo, Hasan Raza Kazmi, Sarah Preston‐Alp…·M. Raza Zaidi

This study identifies a non-canonical melanogenic pathway induced by IFNG that regulates tyrosinase post-translationally, independent of MITF.

1 citation

humanproteomics

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