Michael A. Brehm

This study introduces a novel humanized FLT3 mouse model that supports enhanced development of human innate immune cells and HIV-1 persistence, mimicking human viral reservoirs.

This study investigates bacterial population dynamics in murine tumors, revealing nonuniform growth and a scale-free distribution of bacterial clone sizes.

This study develops a humanized mouse model to investigate the role of innate immunity in FSHD muscle pathology and identifies immune cell accumulation and complement gene expression in FSHD muscle xenografts.

This study shows physical activity reduces breast cancer risk by improving HSC function and enhancing cancer immunosurveillance through reduced oxidative stress and altered T cell differentiation.

The paper identifies bone marrow adipose tissue as a hematopoietic niche that drives pro-inflammatory monocyte production via leptin signaling during aging.