Roop Mallik

The paper shows that dynein teams become collectively inactive under force, allowing kinesin to reverse cargo and regulate bidirectional transport.

This study identifies lysosomal acid lipase (LIPA) as a key enzyme regulating cholesterol metabolism during phagosomal maturation, linking lipid catabolism to antimicrobial defense.

The paper shows that targeting kinesin-1 on lipid droplets reduces serum lipids in cell culture and zebrafish, with no toxicity or lipid accumulation.

This study shows that phosphatidic acid recruits specific motor proteins to lipid bilayers, enabling in-vitro motility and revealing mechanisms of cargo transport and direction reversal.