Author

Carla R. Tirado

The University of Texas Southwestern Medical CenterORCID 0000-0001-6826-6436Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Ariella B. HankeriD· 1 shared Atreyi MukherjiiD· 1 shared Carlos L. ArteagaiD· 1 shared Choushi WangiD· 1 shared Felix Yi-Chung FengiD· 1 shared Ganesh V. RajiD· 1 shared Garrett WainwrightiD· 1 shared Guanghui ZhuiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ariella B. HankerORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer DiscoveryPeer-reviewedApr 8, 2024

ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers

Yaru Xu, Yuqiu Yang, Zhaoning Wang…·Ping Mu

This study shows ZNF397 loss leads to TET2-driven epigenetic changes, lineage plasticity, and resistance to AR-targeted therapies in AR-dependent cancers, with TET2 inhibitors reversing resistance.

50 citationstop 2%

humanbulk RNA-seq

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