Michail N. Isupov

This study uses cryo-EM to show doxycycline binds to the ribosome exit tunnel in C. burnetii and E. coli, revealing new mechanisms of ribosome inhibition.

This study uses cryo-EM to determine the near-atomic structure of the archaeal virus HFTV1, revealing insights into its assembly, infection mechanisms, and host-virus interactions.

The paper uses cryo-electron tomography to reveal structural insights into ribosome hibernation in microsporidian spores, showing ribosome dimers arranged in ordered arrays around the polar tube.

This paper develops an efficient one-step enzymatic method to synthesize cyclic-2,3-diphosphoglycerate using MfcDPGS from Methanothermus fervidus, achieving high conversion efficiency and scalability.

This study shows that SARS-CoV-2 nucleocapsid protein binds to uninfected cells, triggering antibody-mediated complement activation in COVID-19 patients.

This study investigates the catalytic mechanism of methylisocitrate lyase in Coxiella burnetii, identifying key residues and structural changes involved in its function.

The paper presents a cryoEM structure of the archaeal adhesive pilus (Aap) from Sulfolobus acidocaldarius, revealing three distinct conformations of the subunit AapB.

The paper investigates hibernating ribosomes in the microsporidian parasite Spraguea lophii using cryoET and cryoEM, revealing a unique dimeric structure and the role of MDF1 in translation inhibition.