Author
University Medical Center UtrechtORCID 0000-0001-6871-1296Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Anne L. Borst, Francisca J Bergsma, Femke van den Ham…·Judith Wienke
The paper identifies inhibitory Nectin-2/TIGIT interactions between CD163+ macrophages and CD8+ T cells in neuroblastoma tumor niches, linking them to poor patient outcomes.
Thomas A. Kluiver, Anna Nordin, Yuyan Lu…·Weng Chuan Peng
The paper identifies how differential TCF7L2/LEF1 binding specificity of {beta}-catenin shapes distinct gene regulatory outcomes in liver tumors.
Suzanne M. Castenmiller, Anne L. Borst, Leyma Wardak…·Monika C. Wolkers
The paper shows that γδ T cells, not β T cells, are the main anti-tumoral immune cells in pediatric neuroblastoma after chemotherapy.
Maroussia M. P. Ganpat, Francisco Morales-Rodriguez, Nhung Pham…·Jarno Drost
This study creates an engineered tumor organoid model of tRCC using SFPQ-TFE3 fusion expression, revealing epithelium-to-mesenchymal differentiation and Wnt signaling involvement in tumor transformation.
Thomas Alexander Kluiver, Yuyan Lu, Stephanie A Schubert…·Weng Chuan Peng
This study identifies two hepatoblastoma subtypes with distinct WNT activation profiles and discovers drug sensitivities in patient-derived tumor organoids.