Jessica M. A. Blair

The paper shows that a single HTH domain from MarA can bind DNA and activate transcription when properly dimerized, revealing structural insights for synthetic biology applications.

The paper identifies a seventh RND efflux pump, EefABC, in E. coli phylogroups associated with infection, showing high conservation and distinct structural features compared to known systems.

This study shows that MGB-BP-3, a minor groove binder, is more effective against Gram-negative bacteria like E. coli under nutrient-limited conditions than in rich media, with in vivo efficacy in a Galleria mellonella model.

This study compares antibiotic resistance and virulence between Acinetobacter lwoffii and A. baumannii, finding A. lwoffii has fewer resistance genes, more DNA defense systems, and reduced ability to develop resistance.

This study identifies the N-terminal helix of MarA as critical for DNA binding, showing its role in recognizing marboxes and suggesting it as a target for antibiotic resistance inhibitors.

The paper uses dynamic Boolean modeling to show how ATP variability affects efflux pump gene expression in bacteria, revealing energy-dependent heterogeneity in antimicrobial resistance.