Emma R. Holden

This paper uses ICA to analyze TraDIS-Xpress data from E. coli, identifying functional modules of antimicrobial resistance genes across multiple stress conditions.

This study identifies genes critical for Pseudomonas aeruginosa biofilm survival under ciprofloxacin exposure, revealing key pathways and potential therapeutic targets.

The paper investigates how tazobactam affects multidrug resistance in E. coli and Klebsiella pneumoniae using transposon mutagenesis, finding it selects for efflux pumps and membrane permeability changes.

This study uses a whole genome screen to identify genes involved in Salmonella biofilm formation on alfalfa and glass surfaces, revealing distinct mechanisms for each.

This study compares antibiotic resistance and virulence between Acinetobacter lwoffii and A. baumannii, finding A. lwoffii has fewer resistance genes, more DNA defense systems, and reduced ability to develop resistance.

This study shows how four food preservatives exert distinct selective pressures on Salmonella Typhimurium planktonic and biofilm populations, leading to mutations in stress response regulators and trade-offs between biofilm formation and growth.

This study identifies host susceptibility and resistance factors for Salmonella enterica infected by bacteriophages SPLA1a and SPLA5b, showing that their combination reduces phage resistance emergence.

This study identifies the target pathway of a novel antimicrobial compound and discovers synergies with existing antibiotics using genome-wide screening in Gram-negative bacteria.

The paper identifies temporally essential genes for biofilm formation in E. coli using transposon mutagenesis and validates their roles at different stages of biofilm development.