Author
Centre National de la Recherche ScientifiqueORCID 0000-0001-6919-8383Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Diana Olguín-Calderón, Laura E. Kilpatrick, Clément Conil…·Stéphanie Boisson‐Dupuis
Homozygosity for hypomorphic IL23R variants (G149R, G300V, R381Q) partly impairs IL-23-dependent IFN-γ production in patient cells; with L372F (effect inferred), they are enriched in tuberculosis, not MSMD or CMC patients.
Antoine Nouhaud, Diaz Anna, Mathieu Bouttier…·Christine Didier
This study identifies USP7 as a regulator of hematopoietic stem cell dormancy by stabilizing HMGA2, showing its role in maintaining stem cell function and longevity.
Jérémy Bigot, Mathieu Bouttier, Vincent Fregona…·Bastien Gerby
This study identifies CD20 as an actionable target in B-ALL MRD using PDX models and single-cell RNA sequencing, showing anti-CD20 antibodies can eradicate drug-resistant cells.
Laetitia Largeaud, Vincent Fregona, Laura Jamrog…·Cyril Broccardo
This study shows that GATA2 mutations impair HSC function by reducing self-renewal and responsiveness to inflammation, leading to immunodeficiency and myeloid malignancies.