Naïs Prade

This study identifies USP7 as a regulator of hematopoietic stem cell dormancy by stabilizing HMGA2, showing its role in maintaining stem cell function and longevity.

This study identifies CD20 as an actionable target in B-ALL MRD using PDX models and single-cell RNA sequencing, showing anti-CD20 antibodies can eradicate drug-resistant cells.

This study shows that signals from the bone marrow B cell niches influence pre-leukemic cell fate in murine B-ALL by altering proliferation and secondary mutation patterns.

This study shows that GATA2 mutations impair HSC function by reducing self-renewal and responsiveness to inflammation, leading to immunodeficiency and myeloid malignancies.