Margot P. Scheffer

This study uses cryo-electron tomography to analyze structural changes in podocytes during anti-nephrin-mediated kidney disease progression.

The paper uses cryo-electron tomography to reveal the native structure of the human slit diaphragm, showing a fishnet-like lattice with 9 nm spacing, more compact than in mice or Drosophila.

The paper uses advanced imaging techniques to elucidate the molecular architecture of the kidney slit diaphragm, revealing a fishnet-like structure and interactions between key proteins.

This study uses cryo-electron tomography to reveal the bi-layered, fishnet-like architecture of the slit diaphragm in Drosophila nephrocytes, linking its structure to function and conservation across species.

The paper introduces an updated plugin, ArtiaX, for cryo-electron tomography analysis, offering tools for particle selection, camera path definition, and image processing.

This paper reports the structures of Mpn444 and Mpn436, revealing their PPIase and chaperone-like domains and their role in extracellular protein folding in Mycoplasma pneumoniae.