June Fabian

The paper identifies dysregulated proteins in urine from individuals with albuminuria and preserved GFR, linking them to pathways involved in IGF, immunity, and extracellular matrix organization.

This study conducts a GWAS on urinary albumin-to-creatinine ratio in Sub-Saharan African and non-resident African-ancestry populations, identifying two genome-wide significant loci and highlighting limited transferability of polygenic scores across populations.