Jean‐Tristan Brandenburg

This study analyzes breast cancer GWAS across multiple ancestries, finding similar heritability and genetic correlations, and identifies shared regulatory and cellular contexts.

This paper presents an FPGA-based tool for accelerating GWAS permutation testing, achieving significant speed improvements over CPU-based methods like PLINK.

This study conducts a GWAS on urinary albumin-to-creatinine ratio in Sub-Saharan African and non-resident African-ancestry populations, identifying two genome-wide significant loci and highlighting limited transferability of polygenic scores across populations.

This study identifies proteins and pathways linked to hypertension-associated albuminuria using urinary proteomics and machine learning in a South African cohort.

H3AGWAS provides a scalable and portable workflow for conducting GWAS, enabling pre-association, association testing, and post-association analysis with containerized software.

This study identifies genetic variants associated with smoking initiation and cessation in men of African ancestry, highlighting underrepresented populations in genetic research.

The paper analyzes G6PD variant distribution in sub-Saharan Africa and highlights potential risks of using chloroquine/hydroxychloroquine for COVID-19 due to G6PD deficiency.

The paper analyzes the interaction between SARS-CoV-2 RBD and ACE2, identifies key residues for binding, and assesses the impact of ACE2 variants on this interaction.