Özge Ata

This study improves carbon efficiency in autotrophic yeast by redirecting methanol dissimilation through alcohol dehydrogenase, increasing biomass yield and product titers.

This study improves autotrophic growth of engineered Komagataella phaffii through strain optimization and process parameter adjustment, achieving up to 50% faster growth.

This study engineers Komagataella phaffii to produce itaconic acid from methanol, achieving titers of 55 g/L and a yield of 0.24 g/g.

The paper identifies a native phosphoglycolate salvage pathway in Komagataella phaffii that recycles 2-phosphoglycolate, similar to plant pathways, and suggests it can enhance autotrophic growth.