Author
Temple UniversityORCID 0000-0001-7202-1554Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Nicholas Forelli, Trace Thome, Deborah Eaton…·Zoltan Pierre Arany
This study identifies that SGLT2 inhibitors activate pantothenate kinase 1 (PANK1) in the human heart, enhancing coenzyme-A synthesis and fuel use, which may explain their clinical benefits in heart failure.
Apoorva Uboveja, Baixue Yang, Raquel Buj…·Katherine M. Aird
This study shows that αKG-mediated carnitine synthesis supports HR proficiency by promoting histone acetylation, which enhances DNA repair.
Christina Demetriadou, Michael Noji, Austin L. Good…·Kathryn E. Wellen
This study identifies a nuclear branched-chain amino acid catabolism pathway in pancreatic cancer that regulates histone propionylation and gene expression.
Marissa N. Trujillo, Erin Q. Jennings, Emely A. Hoffman…·James J. Galligan
This study shows that lactoylglutathione (LGSH) promotes inflammatory signaling in macrophages by increasing histone lactoylation and chromatin accessibility.