Joseph P. Dewulf

This study shows that SLC5A6 deficiency causes dilated cardiomyopathy in mice, which can be prevented by vitamin supplementation, mirroring clinical outcomes in patients.

This study identifies a NRF2/beta3-adrenoreceptor axis that enhances antioxidant defenses and metabolic rewiring via the pentose-phosphate pathway, protecting cardiac function under stress.

This study introduces a method combining plasma prefractionation and DIA to improve proteome coverage and depth, enabling robust biomarker identification in a COVID-19 cohort.

The paper identifies mutations in the C2orf69 gene as the cause of a human multisystem disorder characterized by autoinflammation, leukoencephalopathy, and hepatopathy.