Laísa Quadros Barsé

This study shows auranofin forms S-Au-S bonds between cysteine thiols in proteins, independent of thioredoxin reductase, suggesting a new mechanism for its antibacterial activity.

This paper investigates how auranofin affects Gram-positive and Gram-negative bacteria, finding that Gram-negative bacteria are more resistant due to efflux systems and glutathione levels.