Edgar Manriquez‐Sandoval

This study shows random 25-mer peptides with a prebiotically plausible amino acid alphabet can self-assemble into thermostable beta-rich nanostructures.

The paper identifies protein surface chemistry as a determinant of desiccation tolerance and shows that modifying surface amino acids can confer tolerance to otherwise sensitive proteins.

FLiPPR improves LiP-MS data analysis by formalizing data imputation, merging data, and correcting multiple hypotheses, enhancing statistical trends and metadata collection.

DomainMapper accurately annotates protein domain structures, including non-contiguous and insertional domains, validated against AlphaFold data.