Author

Shiv K. Sah‐Teli

University of HelsinkiORCID 0000-0001-7285-8522Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Amiel Abettan· 2 shared Esa‐Pekka KumpulaiD· 2 shared Evans EshriewiD· 2 shared Juha T. HuiskoneniD· 2 shared Vivek SharmaiD· 2 shared Amina DjurabekovaiD· 1 shared Ashwini KedariiD· 1 shared Brennan J. WadsworthiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCell Biology

Amiel Abettan

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cell BiologyScience AdvancesPeer-reviewedMay 13, 2026

In situ Structure of the Human Gap Junction

Evans Eshriew, Esa‐Pekka Kumpula, Shiv K. Sah‐Teli…·Juha T. Huiskonen

The paper determines the in situ structure of human Cx43 gap junction plaques using cryogenic electron tomography, revealing the role of the C-terminal domain in plaque assembly.

4 citationstop 3%

humancryo-EM

𝕏 PostBluesky

BiochemistrybioRxivPreprintMay 7, 2026

Gating Mechanism of the Human Connexin 45 Gap Junction Channel

Shiv K. Sah‐Teli, Evans Eshriew, Amiel Abettan…·Juha T. Huiskonen

This study determines the structural basis of Cx45 gating and Ca2+ regulation using cryo-EM, revealing a dual steric-electrostatic mechanism.

DOI 10.64898/2026.05.04.722611

humancryo-EM

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PhysiologyeLifePeer-reviewedNov 24, 2023

A 2-Hydroxybutyrate-mediated feedback loop regulates muscular fatigue

Brennan J. Wadsworth, Marina Leiwe, Eleanor A Minogue…·Randall S. Johnson

This study shows that 2-hydroxybutyrate (2HB) produced during exercise inhibits branched-chain aminotransferases, leading to metabolic changes that enhance oxidative capacity.

11 citations

humanmetabolomics

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