Nathaniel G. Jones

This study identifies KKT2 and CRK9 as essential kinases for Leishmania cell cycle progression using chemical genetics and CRISPR-Cas9.

This study maps the Leishmania ubiquitinome and identifies DUB2 as a key regulator of differentiation by modulating ubiquitination of proteins involved in cell motility and metabolism.

This study characterizes DUB16, an essential UCH family deubiquitinase in Leishmania donovani, showing its structure, activity, and potential as a drug target.

This paper identifies LdBDF5 as a potential drug target for antileishmanial therapy by showing its interaction with human bromodomain inhibitors and demonstrating antipromastigote activity of SGC-CBP30.