Author

Michael J. Shannon

Columbia University Irving Medical CenterORCID 0000-0001-7435-829XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

Emily Margaret MaceiD· 3 shared Adam MoriD· 1 shared Alan R. LoweiD· 1 shared Amera L. MartineziD· 1 shared Carly C. TymmiD· 1 shared Emily K. MooreiD· 1 shared Marianne StrazzaiD· 1 shared Matthieu PaiolaiD· 1 shared

Activity by Year

2024-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

Emily Margaret MaceORCID

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintNov 29, 2024

PAG orchestrates T cell immune synapse function by binding to actin

Emily K. Moore, Marianne Strazza, Xizi Hu…·Adam Mor

This study shows that PAG links to the actin cytoskeleton, and this interaction is essential for T cell synapse formation and cytotoxic function.

DOI 10.1101/2024.11.29.625440

mouseexperimental assay

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Cell BiologyJournal of Cell SciencePeer-reviewedMay 13, 2024

cellPLATO: an unsupervised method for identifying cell behaviour in heterogeneous cell trajectory data

Michael J. Shannon, Shira Esther Eisman, Alan R. Lowe…·Emily Margaret Mace

cellPLATO identifies cell behaviour in trajectory data by clustering morphology and motility metrics, revealing IL-15's role in increasing NK cell migration plasticity.

32 citationstop 3%

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Cell BiologyMolecular Biology of the CellPeer-reviewedMar 20, 2024

CD56/NCAM mediates cell migration of human NK cells by promoting integrin-mediated adhesion turnover

Amera L. Martinez, Michael J. Shannon, Tyler J. Sloan, Emily Margaret Mace

This study shows CD56/NCAM is essential for human NK cell migration by modulating actin dynamics and integrin turnover during movement on stromal cells.

20 citations

humanexperimental assay

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