Julie A. Law

The paper identifies RIM transcription factors that instruct DNA methylation patterns in Arabidopsis reproductive tissues by targeting the RdDM machinery.

This study identifies YAF9A and YAF9B as chromatin readers essential for DNA double-strand break repair in Arabidopsis via homologous recombination pathways.

The paper introduces OM2BFB, an algorithm detecting BFB amplifications using OGMs, showing high precision and recall, and finds BFB events are common in certain cancers but not linked to intratumoral heterogeneity or rapid genome change.

The paper identifies a conserved CYC-YPMF motif in Pol IV critical for CLSY docking, essential for small RNA biogenesis and transposon silencing.

This paper develops a chemoenzymatic method to label non-methylated CpGs in DNA, enabling single-molecule epigenetic profiling in human and plant genomes.

AmpliconReconstructor integrates optical mapping and NGS to resolve focal amplifications in cancer, revealing complex structures and origins of ecDNA and other rearrangements.