Author

Jingbo Dai

Northwestern UniversityORCID 0000-0001-7562-9039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

You‐Yang ZhaoiD· 2 shared Zhiyu DaiiD· 2 shared Dan YiiD· 1 shared Maggie M. ZhuiD· 1 shared Xianming ZhangiD· 1 shared Xinyi ZhangiD· 1 shared Yi Peng· 1 shared Zhiqing Wang· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 20 mutual co-author links

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2 shared papersPathology

You‐Yang ZhaoORCID

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2 papers

Recent·Most cited

PathologybioRxivPreprintAug 2, 2026

CD133+ progenitor cells promote pulmonary hypertension through CXCR4 signaling

Zhiqing Wang, Dan Yi, Xinyi Zhang…·Zhiyu Dai

This study identifies CD133+ progenitor cells as contributors to pulmonary hypertension and shows that CXCR4 signaling drives their pathogenic role in vascular remodeling.

DOI 10.64898/2026.07.29.741640

humanbulk RNA-seq

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PhysiologyJCI InsightPeer-reviewedSep 24, 2024

The Unexpected Role of GCN2 Kinase Activation in Mediating Pulmonary Vascular Remodeling and Pulmonary Arterial Hypertension

Maggie M. Zhu, Jingbo Dai, Zhiyu Dai…·You‐Yang Zhao

This study shows GCN2 kinase activation in hypoxia mediates pulmonary vascular remodeling and PAH via Edn1, suggesting GCN2 as a therapeutic target for PAH.

16 citations

mousehuman

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