Florian L. Müller

The paper identifies acylpeptide hydrolase (APEH) from red blood cells as an enzyme imported by malaria parasites that activates lipophilic ester prodrugs, offering a new strategy to overcome drug resistance.

This paper shows that enolase inhibitors, specifically HEX, are effective against Naegleria fowleri by inhibiting its glycolytic pathway and extending survival in infected rodents.

The paper challenges the assumption that VHL is the target of 3p25 homozygous deletions, showing instead that VGLL4 and ATG7 are the true targets in squamous cell carcinomas and RCC, respectively.