Author

Alexander Stevens

California NanoSystems InstituteORCID 0000-0001-7642-0392Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Z. Hong ZhouiD· 4 shared Ethan H. CrofutiD· 2 shared Saarang KashyapiD· 2 shared Ana L. Alvarez-CabreraiD· 1 shared Jonathan JihiD· 1 shared Katherine A. MuratoreiD· 1 shared Najealicka ArmstrongiD· 1 shared Patricia J. JohnsoniD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMicrobiology

Z. Hong ZhouORCID

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4 papers

Recent·Most cited

MicrobiologyJournal of VirologyPeer-reviewedJul 3, 2025

Structure of a new capsid form and comparison with A-, B- and C-capsids clarify herpesvirus assembly and DNA translocation

Alexander Stevens, Saarang Kashyap, Ethan H. Crofut…·Z. Hong Zhou

This study identifies a new D-capsid type in herpesvirus assembly, revealing structural dynamics of DNA translocation and clarifying the origins of empty and DNA-filled capsids.

5 citations

humancryo-EM

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MicrobiologyNature CommunicationsPeer-reviewedApr 29, 2025

Structures of Native Doublet Microtubules from Trichomonas vaginalis Reveal Parasite-Specific Proteins as Potential Drug Targets

Alexander Stevens, Saarang Kashyap, E. H. Crofut…·Z. Hong Zhou

The paper determines the cryo-EM structure of native Trichomonas vaginalis doublet microtubules, identifying parasite-specific proteins and a potential drug molecule.

9 citations

humancryo-EM

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MicrobiologyVirologyPeer-reviewedMay 17, 2024

Structure-Guided Mutagenesis Targeting Interactions between pp150 Tegument Protein and Small Capsid Protein Identify Five Lethal and Two Live Attenuated HCMV Mutants

Alexander Stevens, Ruth Cruz‐Cosme, Najealicka Armstrong…·Z. Hong Zhou

The paper identifies five lethal and two live attenuated HCMV mutants by mutating pp150-capsid interactions, revealing critical residues for viral replication.

3 citations

humanexperimental assay

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Molecular BiologyProtein & CellPeer-reviewedFeb 4, 2023

Asymmetric Reconstruction of the Aquareovirus Core at Near-Atomic Resolution and Mechanism of Transcriptional Initiation

Alexander Stevens, Yanxiang Cui, Sakar Shivakoti, Z. Hong Zhou

The paper presents the near-atomic structure of the aquareovirus core and reveals structural differences that suggest a mechanism for transcription initiation in multilayered reoviruses.

4 citations

electronic health recordsexperimental assay

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