Trevor Archer

The paper shows that hormone response magnitude in mammary organoids and ER+ cancer cells varies independently of receptor abundance and follows distinct activation dynamics.

The paper shows that loss of H1.4 linker histone affects chromatin accessibility, histone modifications, and gene expression, particularly impacting stress response pathways and immune-related genes.

The paper shows that transcription initiation is not required for histone acetylation and H2AZ incorporation at TSSs but limits their maintenance.

This study shows that PFI-3 enhances iPSC reprogramming by promoting mesenchymal-epithelial transition and reducing extracellular matrix gene expression in human fibroblasts.

This study shows proteasome inhibition changes chromatin accessibility and transcription initiation in breast cancer cells, revealing new insights into how proteasome inhibitors affect gene expression.

This study shows BRG1 is essential for establishing the chromatin landscape in neural progenitor cells, ensuring proper expression of neuroectodermal transcription factors and preventing premature differentiation.