Guido Ferrari

This study shows that a conventional H1 HA trimer vaccine elicits stem-directed antibodies in rhesus macaques that provide broad protection against H1N1 and H5N1 influenza.

This study compares bnAb precursor responses in infant and juvenile rhesus macaques after germline-targeting HIV Env immunization, finding higher rates in infants.

This study engineers an HIV broadly neutralizing antibody to improve its potency, antiviral activity, and manufacturability while maintaining safety and efficacy.

This study evaluates a triple bNAb combination in infant rhesus macaques, showing durable neutralization and effector functions with high predicted prevention efficacy against HIV strains.

This study shows that a multi-dose immunization with germline-targeting SOSIP vaccines induces precursor broadly neutralizing antibodies in infant macaques, similar to adult responses.

This study develops anti-HLA-E-VL9 antibodies that enhance NK and CD8+ T cell cytotoxicity against HIV-infected cells by blocking NKG2A/CD94 interactions and promoting ADCC.