Author

Atsushi Okabe

Chiba UniversityORCID 0000-0001-7748-6078Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Atsushi KanedaiD· 3 shared Ai Katsuma· 1 shared Akari Tojo· 1 shared Akihiro ItoiD· 1 shared Akira SassaiD· 1 shared Atsuhiko FukutoiD· 1 shared Domenico AcciliiD· 1 shared Haruka KobayashiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Atsushi KanedaORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 31, 2025

Breast cancer identity is defined by specialized enhancer sets via lysine deacetylation

Hiroaki Tachiwana, Kohei Kumegawa, Ryota Matsudo…·Noriko Saitoh

The paper identifies hypoacetylation-defined enhancers in luminal breast cancer cells and links them to subtype-specific gene regulation and patient classification.

DOI 10.1101/2025.07.31.668008

humanChIP-seq

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Cell BiologyGenes to CellsPeer-reviewedSep 8, 2024

Dose-dependent effects of histone methyltransferase NSD2 on site-specific double-strand break repair

Koh Iwasaki, Akari Tojo, Haruka Kobayashi…·Kiyoe Ura

This study shows NSD2 has dose-dependent effects on DSB repair pathways, repressing non-c-NHEJ and promoting c-NHEJ while not affecting HR or total NHEJ efficiency.

2 citations

humanChIP-seq

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedNov 3, 2021

An integrative transcriptional logic model of hepatic insulin resistance

Takumi Kitamoto, Taiyi Kuo, Atsushi Okabe…·Domenico Accili

This paper investigates the transcriptional regulation of lipid and glucose metabolic genes in hepatic insulin resistance, finding distinct regulatory patterns and a model for their coexistence in type 2 diabetes.

21 citations

humanbulk RNA-seq

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