Kiyoe Ura

This study examines how SARS-CoV-2 RNA-dependent RNA polymerase replicates past an oxidative RNA lesion, finding that it preferentially incorporates rCMP and has higher bypass efficiency for rA:8-oxo-rG than rC:8-oxo-rG.

This study shows NSD2 has dose-dependent effects on DSB repair pathways, repressing non-c-NHEJ and promoting c-NHEJ while not affecting HR or total NHEJ efficiency.

The paper identifies DNA methylation signatures associated with NSD2 loss-of-function variants and shows their similarity to those in Wolf-Hirschhorn syndrome.

This study investigates how human nucleotide excision repair and DNA polymerase η process single ribonucleotides in DNA, showing their roles in mutagenesis and repair outcomes.