Peiwen Cong

This study evaluates how CD8/CD4 coreceptors affect T cell function by analyzing TCR-pMHC catch and slip bonds, finding that coreceptors enhance bond metrics and TCR sensitivity and specificity.

DynMoCo identifies modular substructures in protein dynamics from molecular simulations by detecting time-evolving communities of residues.

This study shows mechanical force is critical for PD-1 function, as soluble PD-L1 lacks the mechanical support needed to trigger PD-1 signaling.