ImmunologyNature CommunicationsPeer-reviewed
Mechanical force regulates ligand binding and function of PD-1
Kaitao Li, Paul Cárdenas-Lizana, Jintian Lyu…·Cheng Zhu
This study shows mechanical force is critical for PD-1 function, as soluble PD-L1 lacks the mechanical support needed to trigger PD-1 signaling.
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