Mohammad Athar

This study uses human iPSC-derived skin organoids to model fibrosis, identifies RUNX2 as a key driver, and finds a small molecule that suppresses fibrotic programs.

This study shows that mitochondrial-containing sEVs from MDRCs activate and polarize Th17 and Th2 cells in asthma, contributing to airway inflammation.

The paper develops a 3D lung tumor model to evaluate immunotherapy response and identifies biomarkers for predicting immune checkpoint inhibitor efficacy in NSCLC.

The paper identifies common gene regulatory signatures across multiple inflammatory skin diseases using an integrative systems biology framework and proposes potential drug targets.

This study identifies expanded NKT and NK cells with elevated CD2 in HS lesions and shows CD2 blockade reduces inflammation and fibrosis.

The paper compares transcriptome data from SARS-CoV-2 and other respiratory virus infections in human lung epithelial cells to identify genes and pathways associated with SARS-CoV-2 infection.

The paper constructs a human-SARS-CoV-2 interactome using network biology and multiomics data to identify key targets and regulatory circuits involved in SARS-CoV-2 pathogenesis.