Nathan D. Lawson

This study identifies mutations to improve prime editing efficiency in low-dNTP environments by enhancing MMLV-reverse transcriptase and reducing SAMHD1 activity.

The paper develops a protocol to generate floxed alleles in zebrafish for cell-specific knockout, demonstrating its utility in studying gene function.

This study identifies that arterial mural cells provide survival and guidance cues via Cxcl12a/b and Vegfc to promote lymphatic endothelial cell migration in zebrafish.

The paper identifies heterogeneous pdgfrβ+ cells critical for coronary vessel development and heart regeneration in zebrafish.

The paper identifies a conserved pericyte gene signature in zebrafish using scRNA-seq and validates it with transgenic reporter lines.

This study shows that 5' modifications to DNA repair templates enhance precision genome editing efficiency in multiple animal models and human cells.

The paper shows that Pdgfrb signaling is essential for mural cell development in zebrafish, similar to mice, and identifies context-dependent roles in vascular structures.

This study shows that VEGFC induces cell-cycle arrest in endothelial cells, promoting sprouting and differentiation in venous and lymphatic vessels.

The paper traces the morphogenesis and transcriptome of early vascular smooth muscle cells in zebrafish using foxc1b as a marker.