Dose-dependent effects of histone methyltransferase NSD2 on site-specific double-strand break repair
Koh Iwasaki, Akari Tojo, Haruka Kobayashi…·Kiyoe Ura
This study shows NSD2 has dose-dependent effects on DSB repair pathways, repressing non-c-NHEJ and promoting c-NHEJ while not affecting HR or total NHEJ efficiency.