Author

Tackhoon Kim

Korea Institute of Science and TechnologyORCID 0000-0001-7911-6273Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Timothy K. LuiD· 2 shared Benjamin H. WeinbergiD· 1 shared Byung-Sun ParkiD· 1 shared Donghwa KimiD· 1 shared Heeju Jeon· 1 shared Jaeyeal Kim· 1 shared Sang Kook LeeiD· 1 shared So‐Youn JungiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Timothy K. LuORCID

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2 papers

Recent·Most cited

Cancer BiologyeLifePeer-reviewedFeb 28, 2024

Combinatorial CRISPR screen reveals FYN and KDM4 as targets for synergistic drug combination for treating triple negative breast cancer

Tackhoon Kim, Byung-Sun Park, Soobeen Heo…·Timothy K. Lu

The paper identifies FYN and KDM4 as synergistic targets for enhancing TKI efficacy in triple negative breast cancer through CRISPR screens and mechanistic analysis.

10 citations

humangenetic perturbation / CRISPR

𝕏 PostBluesky

Synthetic BiologyNature CommunicationsPeer-reviewedMay 11, 2021

Scalable recombinase-based gene expression cascades

Tackhoon Kim, Benjamin H. Weinberg, Wilson W. Wong, Timothy K. Lu

This paper introduces a modular recombinase-based gene circuit that enables sequential gene expression using two ligands and applies it to model multi-stage genetic changes.

23 citations

experimental assay

𝕏 PostBluesky